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Topic Summary

Posted by: Rachel Delos Reyes
« on: November 30, 2021, 12:35:38 AM »

What is Coronavirus Omicron?

"Omicron" (Omicron) new strain of corona virus. Which was recently discovered and officially confirmed by the World Health Organization or WHO on November 26, 64, and the latest has been classified as a coviral-19 virus. Type 5 mutant that the WHO classifies as a "Worried" strain (Variant of Concern (VOC)) following the alpha, beta, gamma, delta strain.

Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE), which has periodically monitored and evaluated the evolution of SARS-CoV-2, including The mutation assessment states that WHO received the first report of SARS-CoV-2:B.1.1.529 from South Africa on Nov. 24, 64, the first confirmed B.1.1.529 infection. from samples collected on November 9.

Initially, B.1.1.529, or "Omicron," had a shocking accumulation of mutations. And the preliminary evidence suggests an increased risk of reinfection. Compared to other strains of concern (VOC) and current Omicron strains It appears to be increasing rapidly in most parts of South Africa.

However, an examination of the omicron strain found that two mutations on the Spike called Δ69-70 (Amino acid 69-70) were missing, similar to the Alpha strain. As a result, some qPCR laboratories do not detect the S gene, known as S gene target failure or SGTF.

SGTF was originally found only in alpha species. This makes it possible to track omicron species without full genome sequencing, and now the alpha species are almost extinct. Therefore, laboratories can use SGTF as a screening agent for omicron strains. This will make the examination faster.

The TAG-VE team will continue to monitor and assess omicron strains. And if there is more information, it will be updated for member countries and the public to be informed accordingly.

But since the TAG-VE team has presented data indicating dangerous changes in the epidemiology of "Omicron species" WHO would like to warn countries. Increase surveillance for SARS-CoV-2 mutations, exchange information and report infection findings among VOC-associated groups, and reiterate public awareness of spacing. social distance to reduce the risk of infection

It is predicted that there is a genetic change. or effects arising from the nature of the virus, such as transmission of pathogens, disease severity, immune evasion, diagnosis or avoiding treatment Which is still continuing to find proof until now. because it was found that there was a significant transmission of the infection in the community or cluster In many countries, an increase in the number of infected cases over time is associated with an increased prevalence of the disease. or other epidemiological symptoms It has an impact that implies an emerging risk to global public health.

"Virus of concern" (VOC) of the coronavirus. It is a new strain of coronavirus that has been put in the definition. With a comparative assessment method, it was demonstrated to correlate with one or more of the following significant global health scale changes, such as increases. in the transmission of infection or causing harm or damage through epidemiological changes. (germ development) of COVID-19, severity of disease or a change in the clinical manifestations of the disease. or a decline in the effectiveness of public health and social measures. or diagnosis, vaccine, treatment of existing disease

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